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<p>Leptomeningeal metastases (LM) can potentially arise from any solid or haematological tumour. The incidence is certainly underestimated compared to the real figure and therefore, given the aggressiveness and poor prognosis of this clinical entity, it is important to make a diagnosis as soon as possible, which is often complex. In this paper we present a case of LM with extensive cerebellar involvement in a lung adenocarcinoma patient completely asymptomatic.</p>

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Extensive leptomeningeal metastases by lung adenocarcinoma in asymptomatic patient: case report and literature review

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  • 发表日期：

    2025年12月11日

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  • Massimo Della Giustina,
  • Michela Disarò,
  • Piero Sonego,
  • Paolo Sartori

摘要

Leptomeningeal metastases (LM) can potentially arise from any solid or haematological tumour. The incidence is certainly underestimated compared to the real figure and therefore, given the aggressiveness and poor prognosis of this clinical entity, it is important to make a diagnosis as soon as possible, which is often complex. In this paper we present a case of LM with extensive cerebellar involvement in a lung adenocarcinoma patient completely asymptomatic.