Objective <p>This study explores the perception of the word “cancer” among the residents of Jharkhand, India, using a single-question survey approach. The aim was to understand how the term “cancer” is viewed emotionally, culturally, and socially in the region, highlighting prevalent misconceptions and the stigma associated with the disease.</p> Methods <p>This was cross-sectional, descriptive study conducted on total 300 participants who were participants visiting AIIMS, Deoghar OPDs and belongs to both urban and rural areas were surveyed and their face-to-face interviews were conducted and their responses were analyzed.</p> Results <p>The findings revealed that the majority of participant’s associate cancer with fear and death, with only a small portion of individuals expressing hope linked to treatment options. Additionally, 25% of participants described cancer as a taboo subject, pointing to societal stigma and reluctance to discuss the disease openly.</p> Conclusions <p>The study underscores the need for comprehensive public health campaigns focused on cancer education, early detection, and reducing stigma. These efforts are essential to improving awareness, encouraging timely medical intervention, and fostering a more supportive environment for cancer patients in Jharkhand.</p>