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Purpose <p>The optimal reconstruction method following proximal gastrectomy remains controversial. This study aims to compare the short- and long-term outcomes of esophagogastrostomy reconstruction (EGR) and double-tract reconstruction (DTR).</p> Methods <p>We retrospectively collected data from patients who underwent DTR or EGR between June 2014 and January 2020. We compared clinicopathological characteristics and short-term surgical outcomes. Long-term quality of life (QOL) assessments were performed and compared using the Postgastrectomy Syndrome Assessment Scale (PGSAS)-45.</p> Results <p>Thirty-three to 39 patients who underwent DTR and EGR respectively were included in this study. The EGR group had higher body mass index than the DTR group (24.95 ± 3.26 vs. 23.43 ± 2.84, <i>p</i> = 0.039). There was no significant difference between the two groups in terms of surgical safety and feasibility. QOL analysis based on PGSAS-45 showed that the EGR group lost significantly more weight (-17.60% ± 10.00% vs. -12.30% ± 9.60%, <i>p</i> = 0.028) and had lower score of quality of ingestion ((3.04 ± 0.68 vs. 3.45 ± 0.75, <i>p</i> = 0.019). Multivariate analysis suggested that reconstruction mode was independently associated with body weight loss and quality of ingestion score (<i>p</i> &lt; 0.05). There was no significant difference between the two groups in terms of subjective symptom assessment.</p> Conclusion <p>The DTR group showed similar short-term outcomes to the EGR group, and slightly better QOL outcomes. Both reconstruction methods remain optional, and future studies with larger samples will help confirm our findings.</p>

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Short-term and long-term outcomes comparisons between esophagogastrostomy and double tract reconstruction for proximal gastrectomy based on Postgastrectomy Syndrome Assessment Scale (PGSAS)-45 in a Chinese population-based cohort

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  • 出版模式：

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  • 发表日期：

    2026年3月18日

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  • Xiaolong Wu,
  • Yinkui Wang,
  • Fei Shan,
  • Yan Zhang,
  • Fei Pang,
  • Ziyu Li

摘要

Purpose

The optimal reconstruction method following proximal gastrectomy remains controversial. This study aims to compare the short- and long-term outcomes of esophagogastrostomy reconstruction (EGR) and double-tract reconstruction (DTR).

Methods

We retrospectively collected data from patients who underwent DTR or EGR between June 2014 and January 2020. We compared clinicopathological characteristics and short-term surgical outcomes. Long-term quality of life (QOL) assessments were performed and compared using the Postgastrectomy Syndrome Assessment Scale (PGSAS)-45.

Results

Thirty-three to 39 patients who underwent DTR and EGR respectively were included in this study. The EGR group had higher body mass index than the DTR group (24.95 ± 3.26 vs. 23.43 ± 2.84, p = 0.039). There was no significant difference between the two groups in terms of surgical safety and feasibility. QOL analysis based on PGSAS-45 showed that the EGR group lost significantly more weight (-17.60% ± 10.00% vs. -12.30% ± 9.60%, p = 0.028) and had lower score of quality of ingestion ((3.04 ± 0.68 vs. 3.45 ± 0.75, p = 0.019). Multivariate analysis suggested that reconstruction mode was independently associated with body weight loss and quality of ingestion score (p < 0.05). There was no significant difference between the two groups in terms of subjective symptom assessment.

Conclusion

The DTR group showed similar short-term outcomes to the EGR group, and slightly better QOL outcomes. Both reconstruction methods remain optional, and future studies with larger samples will help confirm our findings.