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<p>Cancer remains one of the top causes of mortality globally, as highlighted by the World Health Organization (WHO) and other prominent organizations. Early detection improves treatment outcomes, enhances survival rates, and reduces healthcare costs. Sensors based on nanomaterials facilitate early cancer detection by identifying ultra-low concentrations of biomarkers, which is crucial for effective treatment. Nanomaterials possess unique properties, including exceptional electrical, chemical, thermal, optical, and physical properties. The technology that arises from integrating these nanostructured materials with biosensors is commonly referred to as nanobiosensor technology. Incorporating these sensors into point-of-care devices enables rapid, on-site diagnostics without complex laboratory equipment. Regular monitoring enables the evaluation of therapy success, the implementation of essential changes, and the early identification of recurrence for appropriate intervention. Their detection element primarily determines the specificity and selectivity of nanobiosensors. Nanobiosensors utilize various biological elements, including enzymes, aptamers, antibodies, etc. This review examines recent advancements in nanobiosensors for the early detection of multiple cancer types, such as lung, breast, liver, gynecological, oral, and oesophageal cancers. It also explores the latest therapeutic applications for treatment strategies.</p>

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Nanobiosensor-Based Strategies for Early Cancer Detection and Therapeutic Monitoring

  • 期刊论文

  • 发表日期：

    2026年5月11日

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  • Soumendu Patra,
  • Harshita Shand,
  • Suvankar Ghorai

摘要

Cancer remains one of the top causes of mortality globally, as highlighted by the World Health Organization (WHO) and other prominent organizations. Early detection improves treatment outcomes, enhances survival rates, and reduces healthcare costs. Sensors based on nanomaterials facilitate early cancer detection by identifying ultra-low concentrations of biomarkers, which is crucial for effective treatment. Nanomaterials possess unique properties, including exceptional electrical, chemical, thermal, optical, and physical properties. The technology that arises from integrating these nanostructured materials with biosensors is commonly referred to as nanobiosensor technology. Incorporating these sensors into point-of-care devices enables rapid, on-site diagnostics without complex laboratory equipment. Regular monitoring enables the evaluation of therapy success, the implementation of essential changes, and the early identification of recurrence for appropriate intervention. Their detection element primarily determines the specificity and selectivity of nanobiosensors. Nanobiosensors utilize various biological elements, including enzymes, aptamers, antibodies, etc. This review examines recent advancements in nanobiosensors for the early detection of multiple cancer types, such as lung, breast, liver, gynecological, oral, and oesophageal cancers. It also explores the latest therapeutic applications for treatment strategies.