Scholarlink

<p>This study investigates the correlation between the size and ion release rate of silver nanoparticles (AgNPs) synthesized using tea leaf extract, and their corresponding toxicity levels and antibacterial efficacy. Tea leaf extract served as a green reducing and stabilizing agent, promoting an eco-friendly synthesis route. AgNPs of varying sizes were obtained by manipulating synthesis parameters such as temperature, pH, and extract concentration. Characterization techniques including UV–Vis spectroscopy, Dynamic light scattering (DLS), and Transmission electron microscopy (TEM) were used to assess nanoparticle size, morphology, and dispersion. Ion release was monitored using Inductively coupled plasma optical emission spectroscopy (ICP-OES), and toxicity was evaluated using brine shrimp lethality and plant seed germination assays. Antibacterial activity was tested against <i>Escherichia coli</i> and <i>Staphylococcus aureus</i> using the disk diffusion method. Results indicated a strong size-dependent behavior, where smaller AgNPs exhibited higher ion release and enhanced antibacterial activity but also showed increased toxicity. This suggests that optimizing the size and ion release rate of AgNPs is crucial for balancing efficacy and safety, particularly in biomedical and environmental applications.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Assessment of Toxicity and Antibacterial Activity of Tea Leaf-Extracted Silver Nanoparticles Based on Size and Ion Release Rate

  • 期刊论文

  • 发表日期：

    2025年8月20日

查看全文
  • Vishnu Kumar Khandelwal

摘要

This study investigates the correlation between the size and ion release rate of silver nanoparticles (AgNPs) synthesized using tea leaf extract, and their corresponding toxicity levels and antibacterial efficacy. Tea leaf extract served as a green reducing and stabilizing agent, promoting an eco-friendly synthesis route. AgNPs of varying sizes were obtained by manipulating synthesis parameters such as temperature, pH, and extract concentration. Characterization techniques including UV–Vis spectroscopy, Dynamic light scattering (DLS), and Transmission electron microscopy (TEM) were used to assess nanoparticle size, morphology, and dispersion. Ion release was monitored using Inductively coupled plasma optical emission spectroscopy (ICP-OES), and toxicity was evaluated using brine shrimp lethality and plant seed germination assays. Antibacterial activity was tested against Escherichia coli and Staphylococcus aureus using the disk diffusion method. Results indicated a strong size-dependent behavior, where smaller AgNPs exhibited higher ion release and enhanced antibacterial activity but also showed increased toxicity. This suggests that optimizing the size and ion release rate of AgNPs is crucial for balancing efficacy and safety, particularly in biomedical and environmental applications.