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<p>Biogenic copper nanoparticles (CuNPs) were synthesized using the flower extract of <i>Lantana camara</i> and evaluated for their antioxidant and anticancer activities. The synthesized CuNPs were characterized by several analytical techniques. UV–Visible spectroscopy confirmed nanoparticle formation through surface plasmon resonance (SPR). X-ray Powder Diffraction (XRD) analysis revealed the crystalline structure of the CuNPs. Fourier-Transform Infrared Spectroscopy (FTIR) identified the biomolecules responsible for capping and stabilizing the nanoparticles. Scanning Electron Microscopy (SEM) was employed to examine the morphology and size of the CuNPs, while Energy-Dispersive X-ray Analysis (EDAX) confirmed their elemental composition. The antioxidant activity of the CuNPs was assessed using the DPPH assay, demonstrating a significant free radical scavenging activity with 58.04% inhibition at a concentration of 100&#xa0;µg/ml. The anticancer potential was evaluated against the MDA-MB-231 human breast cancer cell line, where the CuNPs exhibited a notable inhibitory effect on cell proliferation with an IC<sub>50</sub> value of 65.74&#xa0;µg/ml. These results indicate that CuNPs synthesized using <i>L. camara</i> flower extract possess significant antioxidant and anticancer properties, highlighting their potential for therapeutic applications. This study underscores the effectiveness of plant-based methods for nanoparticle synthesis, providing a sustainable approach to developing functional nanomaterials.</p> Graphical Abstract <p></p>

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Biogenic Synthesis of Copper Nanoparticles from Lantana camara Flower Extract: Antioxidant and Anticancer Activities

  • 期刊论文

  • 发表日期：

    2025年5月30日

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  • C. Vigneshwaran,
  • C. Suganya,
  • K. Vasantharaj,
  • Dharamalingam Kirubakaran,
  • C. Sarathi

摘要

Biogenic copper nanoparticles (CuNPs) were synthesized using the flower extract of Lantana camara and evaluated for their antioxidant and anticancer activities. The synthesized CuNPs were characterized by several analytical techniques. UV–Visible spectroscopy confirmed nanoparticle formation through surface plasmon resonance (SPR). X-ray Powder Diffraction (XRD) analysis revealed the crystalline structure of the CuNPs. Fourier-Transform Infrared Spectroscopy (FTIR) identified the biomolecules responsible for capping and stabilizing the nanoparticles. Scanning Electron Microscopy (SEM) was employed to examine the morphology and size of the CuNPs, while Energy-Dispersive X-ray Analysis (EDAX) confirmed their elemental composition. The antioxidant activity of the CuNPs was assessed using the DPPH assay, demonstrating a significant free radical scavenging activity with 58.04% inhibition at a concentration of 100 µg/ml. The anticancer potential was evaluated against the MDA-MB-231 human breast cancer cell line, where the CuNPs exhibited a notable inhibitory effect on cell proliferation with an IC50 value of 65.74 µg/ml. These results indicate that CuNPs synthesized using L. camara flower extract possess significant antioxidant and anticancer properties, highlighting their potential for therapeutic applications. This study underscores the effectiveness of plant-based methods for nanoparticle synthesis, providing a sustainable approach to developing functional nanomaterials.

Graphical Abstract