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<p>Albumin nanoparticles (AlbuNanos) are highly promising approach for delivering drugs directly to the lungs, effectively addressing medical demands that have not yet been satisfied. AlbuNanos are gaining significant interest in the scientific community due to their distinct structural traits, physiological aspects, and biological functions. This paper seeks to offer a thorough examination of the utilization of AlbuNanos in inhalation drug administration, with a specific emphasis on their composition, physical and chemical characteristics, therapeutic uses, and potential future developments. This study commences by providing contextual information on AlbuNanos, encompassing its diverse classifications, with a specific focus on the formulation and process characteristics. The study subsequently examines the therapeutic uses of AlbuNanos and their conjugates, bolstered by data from pharmacokinetic and pharmacodynamic investigations. In addition, the study provides information on the current progress of clinical trials and patents concerning AlbuNanos. The investigation demonstrates that AlbuNanos provide distinct benefits in delivering drugs to the lungs, such as improved drug targeting and prolonged release patterns. Furthermore, the paper examines the present advancements in clinical trials and patents, showcasing the increasing fascination in this pioneering delivery technology. This article presents a comprehensive compilation of information and viewpoints on the various uses of AlbuNanos in delivering drugs to the lungs.</p> Graphical Abstract <p></p>

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Exploring the Albumin Nanoparticles as the Next-Generation Advanced Multifunctional Biomaterials for Inhalation Lung Therapy: Facts, Prospects, and Challenges

  • 期刊论文

  • 发表日期：

    2025年5月12日

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  • Sakshi Kumbhar,
  • Chandrashekhar Bobade,
  • Pallavi Velapure,
  • Datta Pawade,
  • C. Bothiraja,
  • Vaibhav Shinde,
  • Ashwin Mali

摘要

Albumin nanoparticles (AlbuNanos) are highly promising approach for delivering drugs directly to the lungs, effectively addressing medical demands that have not yet been satisfied. AlbuNanos are gaining significant interest in the scientific community due to their distinct structural traits, physiological aspects, and biological functions. This paper seeks to offer a thorough examination of the utilization of AlbuNanos in inhalation drug administration, with a specific emphasis on their composition, physical and chemical characteristics, therapeutic uses, and potential future developments. This study commences by providing contextual information on AlbuNanos, encompassing its diverse classifications, with a specific focus on the formulation and process characteristics. The study subsequently examines the therapeutic uses of AlbuNanos and their conjugates, bolstered by data from pharmacokinetic and pharmacodynamic investigations. In addition, the study provides information on the current progress of clinical trials and patents concerning AlbuNanos. The investigation demonstrates that AlbuNanos provide distinct benefits in delivering drugs to the lungs, such as improved drug targeting and prolonged release patterns. Furthermore, the paper examines the present advancements in clinical trials and patents, showcasing the increasing fascination in this pioneering delivery technology. This article presents a comprehensive compilation of information and viewpoints on the various uses of AlbuNanos in delivering drugs to the lungs.

Graphical Abstract