<p>In this study, a novel pyrazole derivative <b>DCI-1</b> was rationally designed and synthesized using dicyanoisophorone as the fluorophore. The optical properties and recognition performance of <b>DCI-1</b> were systematically investigated. Experimental results verified that the addition of F⁻ induced obvious fluorescence quenching of probe <b>DCI-1</b>, accompanied by a color change of the solution from yellow to colorless. Probe <b>DCI-1</b> exhibits excellent recognition capability toward F⁻ with high selectivity and sensitivity. The limit of detection was calculated to be 1.57 × 10<sup>−7</sup>&#xa0;mol/L. Moreover, the distinct color variation endows <b>DCI-1</b> with outstanding naked-eye recognition ability for F⁻.</p>

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A dicyanoisophorone-based fluorescent probe for highly selective recognition of F⁻

  • Ruonan Xie,
  • Weiguang Zhao,
  • Guihui Li,
  • Tiegang Ren

摘要

In this study, a novel pyrazole derivative DCI-1 was rationally designed and synthesized using dicyanoisophorone as the fluorophore. The optical properties and recognition performance of DCI-1 were systematically investigated. Experimental results verified that the addition of F⁻ induced obvious fluorescence quenching of probe DCI-1, accompanied by a color change of the solution from yellow to colorless. Probe DCI-1 exhibits excellent recognition capability toward F⁻ with high selectivity and sensitivity. The limit of detection was calculated to be 1.57 × 10−7 mol/L. Moreover, the distinct color variation endows DCI-1 with outstanding naked-eye recognition ability for F⁻.