<p>The research examines how corporate governance influences firm value in the sub-Saharan African (SSA) region, focusing on how national governance quality affects this relationship. The study intends to enhance existing knowledge by providing new evidence on corporate governance and the value of firms in countries with weak institutions that are also vulnerable to the effects of global shocks. The research considers a sample size of 309 firms selected from the stock markets of five SSA countries: Botswana, Ghana, Kenya, Nigeria, and South Africa. The study employs a two-stage least squares (2SLS) regression method to analyze the results. The research observes that corporate governance negatively affects firm value, regardless of the firms’ location within the Sub-Saharan Africa region. The study also reveals that when national governance quality is taken into account, the detrimental effects of corporate governance on company value turn into a positive effect in nations with better national governance systems. On the other hand, despite the moderating effect of national governance, businesses in badly run countries still face a negative relationship. The study recommends that regulators and policymakers should encourage firms to fully comply with governance codes by providing robust guidelines, including the establishment of compliance and enforcement mechanisms. Additionally, various governments in the Sub-Saharan Africa region should take proactive measures to address the challenges posed by an unfriendly business climate and political instability.</p>