<p>Studies consistently highlight the pervasive role of entrepreneurship in job creation, enhancing competition, and fostering economic and social development. For this reason, governments encourage entrepreneurship by creating supportive ecosystems for new business formation and growth. Over the past few decades, the Government of Pakistan has facilitated small and medium enterprises (SMEs) by relaxing regulatory frameworks. Despite these advantages and support mechanisms, business owners still face a challenging path toward entrepreneurial success. Numerous studies have attempted to identify the parsimonious factors that contribute to such success. The existing literature emphasizes a variety of social, psychological, personal, and environmental factors as predictors of entrepreneurial outcomes. However, our study primarily developed and tested a serial model comprising predictors, boundary conditions, and underlying mechanisms that lead to entrepreneurial success. A survey questionnaire was administered to owners of small and medium-sized enterprises (SMEs) who had managed businesses and struggled for growth. A substantial response of 350 participants (<i>n</i> = 350) was obtained. The results supported all hypotheses. Theoretical and practical implications are discussed based on the findings.</p>