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<p>The highly exploited medicinal plant <i>Catharanthus roseus</i>, commonly recognized as “Sadabahar” or “Madagascar periwinkle,” is an evergreen flowering medicinal herb that solely belongs to the Apocynaceae family. Earlier, it was also known as <i>Vinca rosea</i>. It is a significant source of <i>Catharanthus</i> alkaloids, commonly referred to as vinca alkaloids, since more than 200 alkaloids are present in it. This highly potent medicinal herb produces pharmaceutically significant TIAs (terpenoid indole alkaloids), including the well-known anti-cancer drugs Vincristine and Vinblastine. Other than alkaloids, phenolic compounds, carbohydrates, proteins, tannins, fats, and oils with pharmacological importance are also present in different parts of the plant. It is becoming more and more popular due to research showing that it contains phytochemicals with different pharmaceutical activities. These include antidiabetic activity, anticancer activity, antiviral, antibacterial, antifungal, antimalarial, antiulcer, antioxidant, hypolipidemic, and wound healing activity. This review provides updated information on the botanical description, geographical distribution, habitat, traditional uses, pharmacological activities, and phytochemical profile of <i>Catharanthus roseus</i> which helps to support the traditional medicinal claims with scientific evidence and helps to identify any gaps that need to be filled in with additional research in the future.</p>

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Catharanthus roseus (L.) G. Don: a concise review on therapeutic uses and pharmacological potential

  • 期刊论文

  • 发表日期：

    2026年7月1日

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  • Aanchal Kumari,
  • Munish Sharma,
  • Munish Sharma

摘要

The highly exploited medicinal plant Catharanthus roseus, commonly recognized as “Sadabahar” or “Madagascar periwinkle,” is an evergreen flowering medicinal herb that solely belongs to the Apocynaceae family. Earlier, it was also known as Vinca rosea. It is a significant source of Catharanthus alkaloids, commonly referred to as vinca alkaloids, since more than 200 alkaloids are present in it. This highly potent medicinal herb produces pharmaceutically significant TIAs (terpenoid indole alkaloids), including the well-known anti-cancer drugs Vincristine and Vinblastine. Other than alkaloids, phenolic compounds, carbohydrates, proteins, tannins, fats, and oils with pharmacological importance are also present in different parts of the plant. It is becoming more and more popular due to research showing that it contains phytochemicals with different pharmaceutical activities. These include antidiabetic activity, anticancer activity, antiviral, antibacterial, antifungal, antimalarial, antiulcer, antioxidant, hypolipidemic, and wound healing activity. This review provides updated information on the botanical description, geographical distribution, habitat, traditional uses, pharmacological activities, and phytochemical profile of Catharanthus roseus which helps to support the traditional medicinal claims with scientific evidence and helps to identify any gaps that need to be filled in with additional research in the future.