<p>Avian influenza viruses, particularly H9N2 and H5N1 viruses, pose serious health hazards to people since they can cause severe respiratory illnesses and high death rates. The investigation of alternative therapeutics has been prompted by the limits of traditional antiviral treatments, including resistance and side effects. Herbal remedies, which have been utilized historically and empirically in many different cultures, are viable choices for treating these viral infections in addition to or instead of conventional therapies. This paper aims to investigate the effectiveness and ensure the safety of several herbal therapies in the management of human infections caused by H9N2 and H5N1. The principal modes of action of the plant, including their antiviral, immune-stimulating, and anti-inflammatory properties, have demonstrated encouraging potential in combating avian influenza. Additionally, these plants show promise as a synergistic alternative to traditional antiviral medications. In order to demonstrate their efficacy against the virus, clinical trials and case reports were analyzed. This review also addresses the incorporation of herbal remedies into traditional treatment plans, emphasizing the significance of quality control and standardized dosing. In conclusion, this study emphasizes the potential of herbal remedies as potent defenses against avian influenza viruses and encourages their use in broad therapeutic protocols to enhance public health resilience and improve patient outcomes.</p> Graphical Abstract <p></p>