<p>Crohn’s disease and ulcerative colitis are immune-mediated gastrointestinal disorders commonly referred to as inflammatory bowel diseases. The etiology of the disease involves both environmental and inherited components. For gastroenterologists and traditional surgeons, managing it poses constant hurdles. It has been discovered that the toxicity that 5-aminosalicylates, steroids, and antibiotics are said to induce deters people from using them. It has been observed that coumarin and its derivatives are anti-inflammatory and antioxidant substances that may be helpful as a supplemental treatment for inflammatory bowel disease. Via various processes and signaling pathways, these substances mitigate intestinal inflammation by primarily regulating immunological and inflammatory responses and shielding the body from oxidative stress, which is a major contributing factor to the development of inflammatory bowel diseases. Research indicates that many anti-inflammatory phytochemicals may become novel therapeutics for the treatment of inflammatory bowel diseases. Because most of phytochemicals are non-toxic, have fewer adverse effects than allopathic drugs, and function through a variety of pathways and sites of action, their use is risk-free. The usefulness of several pathways as a current therapeutic target for inflammatory bowel disease is covered in this review. Additional preclinical and clinical studies are needed to elucidate the molecular mechanism to advance the clinical use of phytochemicals for inflammatory bowel diseases.</p> Graphical Abstract <p></p>