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<p>Major advances in biomedical science have transformed healthcare. However, system barriers to the appropriate, timely, and equitable use of biomedical innovations have led to slow and inconsistent adoption, limiting and delaying our ability to leverage their full potential to improve health. System barriers include inconsistent coverage, imperfect information systems for decision making and real word evidence, policy constraints, system capacity, social influences on health, and infrastructure gaps.</p><p>We propose the development of an open access dynamic design “engine” to align biomedical and health system innovation. This engine will include coordinated collaborative design processes, frameworks, and tools, developed with input from all stakeholders, and centered around two critical, interdependent capabilities: (1) system design and (2) impact measurement. These capabilities will build capacity for efficient, model-driven design and implementation planning of sustainable, patient centered system innovations.</p><p>The stakes are high for both the clinical promise of transformational products and their budget impact. Our current healthcare system is not ready to maximize benefit from transformational science and emerging biomedical innovations. We need to help the healthcare system catch up with the science.</p>

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Optimizing Biomedical Health Efficiency: Unlocking the Full Potential of Life Science Innovation Through System Design

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年7月26日

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  • Gigi Hirsch,
  • Sharon E. Phares,
  • Jane Barlow,
  • Murray Aitken,
  • Mark Cziraky,
  • Gregory Daniel,
  • Chester Good,
  • Annie Kennedy

摘要

Major advances in biomedical science have transformed healthcare. However, system barriers to the appropriate, timely, and equitable use of biomedical innovations have led to slow and inconsistent adoption, limiting and delaying our ability to leverage their full potential to improve health. System barriers include inconsistent coverage, imperfect information systems for decision making and real word evidence, policy constraints, system capacity, social influences on health, and infrastructure gaps.

We propose the development of an open access dynamic design “engine” to align biomedical and health system innovation. This engine will include coordinated collaborative design processes, frameworks, and tools, developed with input from all stakeholders, and centered around two critical, interdependent capabilities: (1) system design and (2) impact measurement. These capabilities will build capacity for efficient, model-driven design and implementation planning of sustainable, patient centered system innovations.

The stakes are high for both the clinical promise of transformational products and their budget impact. Our current healthcare system is not ready to maximize benefit from transformational science and emerging biomedical innovations. We need to help the healthcare system catch up with the science.