<p>This study investigates the spatio-temporal variations of depositional lithofacies within the Middle and Upper Eocene succession (Cherahil Formation and its stratigraphic equivalents) in the Gulf of Gabes (southeastern Tunisia). Based on lithological and well log data from 26 wells, a detailed chronostratigraphic framework was established. Isofacies maps for the Early Lutetian, Upper Lutetian, and Upper Lutetian-Priabonian intervals reveal that lithofacies are organized into NW-SE-oriented belts, likely influenced by synsedimentary faults. Shallow-water, open-marine facies developed on uplifted structures, whereas deeper-water, low-energy facies accumulated in paleodepressions. Localized lithofacies, such as patch reefs and glauconite- and organic matter-rich deposits, reflect variations in hydrodynamic conditions. The Early Lutetian and the Upper Lutetian-Priabonian intervals show evidence of tectonic activity, associated with pronounced lateral facies variations, while during the Upper Lutetian, fault activity appears to have been reduced, coinciding with a more uniform carbonate sedimentation. These results highlight an important role of tectono-structural controls in shaping a dissected Eocene carbonate platform in the Gulf of Gabes (southeastern Tunisia), suggesting a more complex platform morphology than the previously proposed simple homoclinal ramp model, and providing new insights into the regional paleogeographic evolution of the Eocene deposits and their sedimentary architecture, with potential implications for petroleum exploration in the area.</p>