Scholarlink

<p>A monolayer model with three energies, developed based on statistical physics, was applied to analyze the adsorption mechanisms of sotolone and abhexone on the human olfactory receptor OR8D1. The first type of binding site played a dominant role in this food odorant mechanism, with OR8D1 binding sites arranged in non-parallel orientations, indicating a multimolecular process. Molar adsorption energies associated with the three types of binding sites, ranging from 23.75 to 32.97&#xa0;kJ mol<sup>− 1</sup>, demonstrated that the food odorants were physically and exothermically adsorbed on the human OR8D1 receptor.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Theoretical investigation of human olfactory receptor OR8D1 activated by two key food odorants

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2026年2月26日

查看全文
  • Ismahene Ben Khemis,
  • Fatma Aouaini,
  • Salah Knani,
  • Ana Carolina Ferreira Piazzi Fuhr,
  • Ghadeer Mohsen Albadrani,
  • Franciele da Silva Bruckmann,
  • GuilhermeLuiz Dotto,
  • Abdelmottaleb Ben Lamine

摘要

A monolayer model with three energies, developed based on statistical physics, was applied to analyze the adsorption mechanisms of sotolone and abhexone on the human olfactory receptor OR8D1. The first type of binding site played a dominant role in this food odorant mechanism, with OR8D1 binding sites arranged in non-parallel orientations, indicating a multimolecular process. Molar adsorption energies associated with the three types of binding sites, ranging from 23.75 to 32.97 kJ mol− 1, demonstrated that the food odorants were physically and exothermically adsorbed on the human OR8D1 receptor.