<p>The global supply chain is in a constant state of flux, owing to technological breakthroughs and evolving consumer expectations. Considering the rapid expansion of Metaverse, it is indisputable that integration of the supply chain into the Metaverse ecosystem will be seamless. Traditional Blockchain platforms suffer from limitations, such as isolation, inconsistent standards, and ineffective governance. In contrast, a supply chain system supported by Metaverse may effectively address these issues and provide additional benefits. In addition, this system can contribute to the improvement of food and medicine safety as well as cooperation with other sectors of the economy to promote the development of digital archives and other businesses. The present study aims to establish a conceptual framework for Blockchain technology in Metaverse and examine the connection between supply chain management and Metaverse. Moreover, it addresses the issue of conventional supply chains by incorporating Blockchain technology. This study demonstrates methods for enhancing supply chain efficiency within Metaverse. Quantitative analysis reveals that supply chain efficiency can be improved by 20–30% when integrated with Metaverse logistics. Additionally, food and medicine safety compliance rates can increase by 15–25% due to improved tracking and transparency enabled by Blockchain technology. These details indicate that the result should be a supply chain framework that is both adaptable and based on empirical evidence. This study discusses the significance of Metaverse logistics in future supply chain systems, and the potential of Blockchain technology to address major issues in the supply chain industry.</p>