<p>With the prevalence of hospital-acquired infection rates and increased indoor air contamination with microbes worldwide, effective air purification solutions are required. Traditional methods such as High-Efficiency Particulate Air filters and Ultraviolet systems are costly, require high maintenance, or pose health risks. Negative air ions (NAIs) provide an alternative non-invasive solution by removing microbes and allergens through oxidative damage and precipitation. This study evaluated the effectiveness of a new NAI generator, “Instashield,” as an indoor air purifier in a tertiary hospital and a Good Laboratory Practice (GLP)-certified laboratory in Hyderabad, India. In hospital settings, after 1&#xa0;h of NAI exposure, bacterial colony forming unit (CFU) reduction ranged from 32.04 to 38.34%, and fungal CFU reduction ranged from 35.82 to 77.78%, with the highest reductions observed in the intensive care unit. In the GLP laboratory, bacterial and fungal CFU reductions reached 99.6% and 100%, respectively, after 36&#xa0;h, with no growth of <i>Escherichia coli</i>,<i> Salmonella enterica</i>,<i> Staphylococcus aureus</i>, and <i>Pseudomonas aeruginosa</i> after 12&#xa0;h. The device showed stable performance under varying environmental conditions, with CO<sub>2</sub> emissions from the device decreasing from 450 ppm to 410 ppm within 24&#xa0;h, well within the safe indoor air quality threshold of 600 ppm. These findings validate Instashield as an effective, non-invasive air purifier to prevent nosocomial infection and maintain indoor air quality. Further research is required to assess its efficacy under different environmental conditions and against a broader range of pathogens, including viruses.</p>

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Effectiveness of a negative ion generator “Instashield” for indoor air disinfection: evidence from tertiary care hospital and GLP laboratory settings

  • Neema Kumari,
  • Vikas Sahu,
  • Kavya Chintala,
  • Swathi C. M.,
  • Chandra Sri Durga,
  • Hima Bindu Mantravadi,
  • Palavardhan Peddapalegani,
  • Kranti Kiran Reddy Ealla

摘要

With the prevalence of hospital-acquired infection rates and increased indoor air contamination with microbes worldwide, effective air purification solutions are required. Traditional methods such as High-Efficiency Particulate Air filters and Ultraviolet systems are costly, require high maintenance, or pose health risks. Negative air ions (NAIs) provide an alternative non-invasive solution by removing microbes and allergens through oxidative damage and precipitation. This study evaluated the effectiveness of a new NAI generator, “Instashield,” as an indoor air purifier in a tertiary hospital and a Good Laboratory Practice (GLP)-certified laboratory in Hyderabad, India. In hospital settings, after 1 h of NAI exposure, bacterial colony forming unit (CFU) reduction ranged from 32.04 to 38.34%, and fungal CFU reduction ranged from 35.82 to 77.78%, with the highest reductions observed in the intensive care unit. In the GLP laboratory, bacterial and fungal CFU reductions reached 99.6% and 100%, respectively, after 36 h, with no growth of Escherichia coli, Salmonella enterica, Staphylococcus aureus, and Pseudomonas aeruginosa after 12 h. The device showed stable performance under varying environmental conditions, with CO2 emissions from the device decreasing from 450 ppm to 410 ppm within 24 h, well within the safe indoor air quality threshold of 600 ppm. These findings validate Instashield as an effective, non-invasive air purifier to prevent nosocomial infection and maintain indoor air quality. Further research is required to assess its efficacy under different environmental conditions and against a broader range of pathogens, including viruses.