Antimicrobial and antibiofilm activities of Brazilian organic honey against oral microorganisms

期刊论文
发表日期：

2024年5月15日

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Diego Romário-Silva,
Marcelo Franchin,
Severino Matias Alencar,
Bruno Bueno-Silva,
Janaína de Cássia Orlandi Sardi,
Andréa Cristina Barbosa da Silva,
Fabiane Cruz-Vieira,
Priscila Vieira da Silva,
Pedro Luiz Rosalen

摘要

Objective

To evaluate the antimicrobial activity of Brazilian honeys against oral microorganisms. Design: Organic honeys (OH-1 to OH-8) were diluted (%-w/v) and sterilized by filtration. Antimicrobial activity was defined by determining MIC and CBM against oral Streptococcus. The component responsible for the antimicrobial action was defined by a catalase assay. Antibiofilm activity was evaluated against the monospecies biofilm of Streptococcus mutans (ATCC 700610).

Results

OHs showed antimicrobial activity principally OH-1, OH-2, OH-3, and OH-7 with MIC values ranging between 10 and 25%. The mechanism of action occurs mainly by hydrogen peroxide produced by honey enzymes. OH-1, OH-2, and OH-7 showed total biofilm destruction at low concentrations.

Conclusion

Brazilian honeys have promising antimicrobial and antibiofilm activity with the potential to control oral microbiota.