Description of Corynebacterium hiratae sp. nov. isolated from a human tissue bone a novel member of Corynebacterium Genus

期刊论文
发表日期：

2024年4月10日

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Lincoln de Oliveira Sant’Anna,
Louisy Sanches dos Santos,
Julianna Giordano Botelho Olivella,
Mariana da Cruz Mota,
Juliana Nunes Ramos,
Paulo Victor Pereira Baio,
Danilo Jobim Passos Gil da Rocha,
Verônica Viana Vieira,
Marisa Almuzara,
Carlos Vay,
Claudia Barberis,
Thiago Luiz de Paula Castro,
Núbia Seyffert,
Luis Gustavo Carvalho Pacheco,
Ana Luíza Mattos-Guaraldi

摘要

Background

Corynebacterium spp. are widely disseminated in the environment, and they are part of the skin and mucosal microbiota of animals and humans. Reports of human infections by Corynebacterium spp. have increased considerably in recent years and the appearance of multidrug resistant isolates around the world has drawn attention.

Objectives

To describe a new species of Corynebacterium from human tissue bone is described after being misidentified using available methods.

Methods

For taxonomic analyses, phylogenetic analysis of 16S rRNA and rpoB genes, in silico DNA-DNA hybridization, average nucleotide and amino acid identity, multilocus sequence analysis, and phylogenetic analysis based on the complete genome were used.

Findings

Genomic taxonomic analyzes revealed values of in silico DNA-DNA hybridization, average nucleotide and amino acids identity below the values necessary for species characterization between the analyzed isolates and the closest phylogenetic relative Corynebacterium aurimucosum DSM 44532^T.

Main conclusions

Genomic taxonomic analyzes indicate that the isolates analyzed comprise a new species of the Corynebacterium genus, which we propose to name Corynebacterium hiratae sp. nov. with isolate 332^T (= CBAS 826^T = CCBH 35,014^T) as the type strain.