Purpose <p>The primary objective of this study was to address the challenges associated with nitrogen management in soils characterized by low organic matter content, where substantial fertilizer losses contribute to reduced wheat yield and increased environmental degradation.</p> Method <p>A foliar application experiment was conducted involving twelve distinct treatments comprising combinations of three levels of humic acid (0, 2, and 4 Kg ha⁻¹) and four concentrations of inorganic nitrogen, phosphorus, and potassium fertilizer (0, 0.5, 1.0, and 2.0%). The aim was to identify the most effective treatment combination for enhancing the growth and yield performance of wheat.</p> Result <p>The findings indicated that the integrated treatment involving 2.0% inorganic nitrogen, phosphorus, and potassium fertilizer combined with 4 Kg ha⁻¹ of humic acid significantly improved both biological and grain yield relative to the control and sole applications of humic acid. Notably, the nitrogen content in grain increased by 37.63%, 16.49%, and 20.82% compared to the control (0% nitrogen, phosphorus, and potassium), 2 Kg ha⁻¹ humic acid, and 4 Kg ha⁻¹ humic acid treatments, respectively.</p> Conclusion <p>It is concluded that the combined application of 2.0% inorganic nitrogen, phosphorus, and potassium fertilizer with 4 Kg ha⁻¹ of humic acid represents the most effective strategy for enhancing wheat yield and nutrient uptake. However, additional field-level research across diverse soil textures and wheat cultivars is recommended to confirm its consistency and to support broader agronomic recommendations.</p>