<p>Mineral liberation, locking, and exposure are directly linked to the performance of processes such as leaching and flotation. Comminution is performed prior to subsequent separation steps to increase mineral liberation and exposure that are necessary for efficient mineral separation and leaching. Correspondingly, there is an important relationship between comminution and mineral liberation, locking, and exposure. This paper reviews important equations that can be used to calculate mineral liberation, locking, and exposure and the associated impact of comminution on these characteristics. Using the Rosin-Rammler distribution function, we have developed a methodology to estimate the liberated fraction of valuable minerals. Additionally, we derived equations to model scenarios involving fully locked and partially locked mineral particles, providing a comprehensive framework for understanding mineral liberation. Furthermore, the impact of host particle size reduction on the size distribution of valuable mineral particles has been analyzed, shedding light on the relationship between comminution processes and mineral liberation efficiency. These calculations can be used to enable the prediction of subsequent processing steps such as leaching and flotation, which depend heavily on the fraction of material that is liberated, locked, and exposed.</p>