Purpose <p>In this paper, we have studied the isolation of vibrations in the plane normal to the LOS (line of sight), which is the main cause of the LOS deviation of a high-resolution satellite optical camera.</p> Method <p>To isolate micro-vibrations that are the main cause of the LOS deflection, a novel two-dimensional vibration isolation system consisting of three QZS (quasi-zero stiffness) are proposed. The stiffness characteristic of a two-dimensional vibration isolation system with three QZS was analyzed. To verify the effectiveness of the proposed 2D vibration isolation system using the newly proposed QZS system, the vibration isolation characteristics analysis from the reaction wheel, which is the main source of the micro-vibration, to the second mirror center of the optical camera, with two different vibration isolation systems, was carried out through simulation analysis. In addition, a comparative analysis of the newly proposed two-dimensional quasi-zero stiffness vibration isolation system and the vibration isolation methods presented in previous studies is carried out for a more extensive discussion.</p> Result <p>The analysis shows that the vibration isolation system using QZS reduces the vibration by 98.89% in the X-direction and 91.54% in the Y-direction than the vibration isolation system with linear springs. Also, the vibration reduction in X-direction is 97.65% and Y-direction 87.75% compared to the vibration isolation system using viscoelastic materials proposed in the previous study.</p> Conclusion <p>The two-dimensional quasi-zero stiffness vibration isolation system consisting of three quasi-zero stiffness elements rarely transmit vibration and is crucial for maintaining high resolution satellite optical cameras.</p>