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Background <p>Blood transfusions are vital for patient treatment, particularly in critical environments. Adverse occurrences subsequent to transfusions underscore the necessity for robust haemovigilance systems. This study sought to examine transfusion-related responses documented at a tertiary care hospital in Northeast India.</p> Methods <p>A 9-month observational cross-sectional research documented blood transfusion reactions using HvPI forms and classified them per AABB criteria. Descriptive statistics and Fisher’s exact test (<i>P</i> &lt; 0.05) were used.</p> Results <p>Among 101 transfusion recipients, females constituted 61.38%, with blood groups A positive (31.68%) and B positive (26.73%) being most common. Acute reactions (70.29%) were frequently reported, predominantly by the medicine department (60.39%). Non-severe reactions were prevalent (96.03%), with no permanent disabilities or deaths. Of 45,200 transfusion units, whole blood was most frequently used (48.98%) and had the highest reaction risk (0.28%). Allergic reactions (37.62%) were most prevalent, after that Febrile Non-Hemolytic Transfusion Reactions (FNHTR) (33 cases), with most reactions occurring within the first 100&#xa0;ml of transfusion.</p> Conclusion <p>The predominance of non-severe reactions and absence of severe outcomes highlight the effectiveness of current haemovigilance protocols. However, the need for heightened vigilance during initial transfusion stages is crucial to promptly identify and manage adverse reactions.</p> Graphical Abstract <p></p>

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A Nine-Month Observational Study at a Tertiary Care Hospital in Northeast India Examining Patterns and Outcomes of Transfusion-Related Reactions

  • 期刊论文

  • 发表日期：

    2026年6月18日

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  • Mudasir Maqbool,
  • Zulfkar Latief Qadrie,
  • Amita Joshi Rana,
  • Jyoti Maithani Kalra,
  • Baby Ilma,
  • Yumna Khan,
  • Sumel Ashique,
  • Md Sadique Hussain

摘要

Background

Blood transfusions are vital for patient treatment, particularly in critical environments. Adverse occurrences subsequent to transfusions underscore the necessity for robust haemovigilance systems. This study sought to examine transfusion-related responses documented at a tertiary care hospital in Northeast India.

Methods

A 9-month observational cross-sectional research documented blood transfusion reactions using HvPI forms and classified them per AABB criteria. Descriptive statistics and Fisher’s exact test (P < 0.05) were used.

Results

Among 101 transfusion recipients, females constituted 61.38%, with blood groups A positive (31.68%) and B positive (26.73%) being most common. Acute reactions (70.29%) were frequently reported, predominantly by the medicine department (60.39%). Non-severe reactions were prevalent (96.03%), with no permanent disabilities or deaths. Of 45,200 transfusion units, whole blood was most frequently used (48.98%) and had the highest reaction risk (0.28%). Allergic reactions (37.62%) were most prevalent, after that Febrile Non-Hemolytic Transfusion Reactions (FNHTR) (33 cases), with most reactions occurring within the first 100 ml of transfusion.

Conclusion

The predominance of non-severe reactions and absence of severe outcomes highlight the effectiveness of current haemovigilance protocols. However, the need for heightened vigilance during initial transfusion stages is crucial to promptly identify and manage adverse reactions.

Graphical Abstract