Ossified Airways with Pulmonary Tuberculosis: A Rare Coexistence—A Case Series of Three Patients
摘要
Tracheobronchopathia osteochondroplastica (TBO) is a rare, benign condition characterized by the presence of submucosal bony and cartilaginous nodules along the anterolateral wall of the tracheobronchial tree. Its resemblance to other endobronchial pathologies, including tuberculosis, can make diagnosis challenging. Although some reports suggest an association between TBO and chronic infections like pulmonary tuberculosis (PTB), the causal relationship remains unclear.
Case DescriptionWe describe three patients with concurrent TBO and PTB who presented with respiratory and constitutional symptoms. Imaging revealed pulmonary lesions typical of tuberculosis. Bronchoscopy showed characteristic whitish nodules with sparing of the posterior wall, suggestive of TBO. Histopathology confirmed the diagnosis in two cases. PTB was confirmed by BAL analysis (AFB staining or CBNAAT). All patients responded well to standard anti-tuberculous therapy.
ConclusionThis series highlights the rare coexistence of TBO and PTB. Recognition of typical bronchoscopic features is crucial for diagnosis, and awareness of this condition is important to avoid misdiagnosis and unnecessary interventions.