Scholarlink

Background <p>Microtia is a congenital anomaly of the external ear that may occur in isolation or as part of syndromic conditions involving multiple organ systems. Due to shared embryological origins between craniofacial and renal structures, studies have suggested a potential association with genitourinary anomalies. However, data from Latin American populations remain limited.</p> Methods <p>This cross-sectional observational study included 146 Ecuadorian patients with microtia who underwent abdominal ultrasound screening in 2024. Patients were classified as having isolated or familial microtia. Renal morphology was assessed using standardized measurements, including kidney length, cortical thickness, and volume. Hepatic and gallbladder findings were also recorded. Data were analyzed using descriptive statistics and non-parametric tests.</p> Results <p>Among the 146 patients, 28 (19.8%) exhibited abnormal abdominal ultrasound findings. The most common anomalies were fatty liver (39.3%), renal pelvis ectasia (35.7%), and double collecting system (17.9%). Males represented 67.9% of affected individuals. The kidneys were the most frequently involved organ (46.4%), followed by the liver (32.1%) and gallbladder (14.3%). Comparative analysis showed no statistically significant differences in renal parameters across microtia subtypes. Although percentile-based classifications were applied, the lack of a control group limited interpretation of prevalence.</p> Conclusions <p>A substantial proportion of microtia patients presented with renal and hepatic abnormalities. While no significant renal morphological differences were found between microtia types, the findings support the need for abdominal screening in selected cases. Future studies with control groups and metabolic profiling are needed to clarify potential syndromic or developmental associations.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Beyond the Ear: Uncovering Renal, Hepatic, and Gallbladder Abnormalities in Patients with Microtia

  • 期刊论文

  • 发表日期：

    2025年8月23日

查看全文
  • Fabricio González-Andrade,
  • Eduardo Yépez-García,
  • Giovanna Narváez-Miranda,
  • Fausto Coello,
  • Henry Vásconez

摘要

Background

Microtia is a congenital anomaly of the external ear that may occur in isolation or as part of syndromic conditions involving multiple organ systems. Due to shared embryological origins between craniofacial and renal structures, studies have suggested a potential association with genitourinary anomalies. However, data from Latin American populations remain limited.

Methods

This cross-sectional observational study included 146 Ecuadorian patients with microtia who underwent abdominal ultrasound screening in 2024. Patients were classified as having isolated or familial microtia. Renal morphology was assessed using standardized measurements, including kidney length, cortical thickness, and volume. Hepatic and gallbladder findings were also recorded. Data were analyzed using descriptive statistics and non-parametric tests.

Results

Among the 146 patients, 28 (19.8%) exhibited abnormal abdominal ultrasound findings. The most common anomalies were fatty liver (39.3%), renal pelvis ectasia (35.7%), and double collecting system (17.9%). Males represented 67.9% of affected individuals. The kidneys were the most frequently involved organ (46.4%), followed by the liver (32.1%) and gallbladder (14.3%). Comparative analysis showed no statistically significant differences in renal parameters across microtia subtypes. Although percentile-based classifications were applied, the lack of a control group limited interpretation of prevalence.

Conclusions

A substantial proportion of microtia patients presented with renal and hepatic abnormalities. While no significant renal morphological differences were found between microtia types, the findings support the need for abdominal screening in selected cases. Future studies with control groups and metabolic profiling are needed to clarify potential syndromic or developmental associations.