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Background <p>Squamous cell carcinoma (SCC) of the larynx is very rare in adolescents, with only a few case reports. The exact pathogenesis is still an area of research; however, some known predisposing factors reported earlier include high-risk HPV infection, chemotherapy, and radiotherapy exposure for other primary pediatric malignancies. The diagnosis may be delayed due to a low index of suspicion and overlapping presentation with other more common malignant as well as benign conditions.</p> Case Presentation <p>A young 15-year-old child, apparently alright, presented with an insidious pus-discharging swelling in the anterior neck. Repeated incision and drainage were done. On radiology, an ill-defined enhancing lesion was noted in the glottis with necrotic cervical nodes. Fine needle aspiration cytology (FNAC) was repeated twice and reported as an inflammatory epidermal inclusion cyst. However, biopsy revealed an infiltrating squamous cell carcinoma. The child received 3 cycles of chemotherapy with a marked reduction in size, to be subsequently followed by radiotherapy.</p> Conclusions <p>We are reporting a case of HPV negative laryngeal squamous cell carcinoma in a 15-year-old young child, with a unique presentation of pus discharge resulting in multiple incisions and drainage and delayed diagnosis.</p>

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A Unique Case of Squamous Cell Carcinoma Larynx in a 15-Year-Old Boy Camouflaging as an Abscess with Pus Discharging Sinus Tract: A Case Report

  • 期刊论文

  • 发表日期：

    2025年7月30日

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  • Rakesh Kumar Gupta,
  • Satish S Satpute,
  • Amit Kumar Chowhan,
  • Mudalsha Ravina,
  • Amit Kumar,
  • Manish Kumar

摘要

Background

Squamous cell carcinoma (SCC) of the larynx is very rare in adolescents, with only a few case reports. The exact pathogenesis is still an area of research; however, some known predisposing factors reported earlier include high-risk HPV infection, chemotherapy, and radiotherapy exposure for other primary pediatric malignancies. The diagnosis may be delayed due to a low index of suspicion and overlapping presentation with other more common malignant as well as benign conditions.

Case Presentation

A young 15-year-old child, apparently alright, presented with an insidious pus-discharging swelling in the anterior neck. Repeated incision and drainage were done. On radiology, an ill-defined enhancing lesion was noted in the glottis with necrotic cervical nodes. Fine needle aspiration cytology (FNAC) was repeated twice and reported as an inflammatory epidermal inclusion cyst. However, biopsy revealed an infiltrating squamous cell carcinoma. The child received 3 cycles of chemotherapy with a marked reduction in size, to be subsequently followed by radiotherapy.

Conclusions

We are reporting a case of HPV negative laryngeal squamous cell carcinoma in a 15-year-old young child, with a unique presentation of pus discharge resulting in multiple incisions and drainage and delayed diagnosis.