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<p>Surgical interventions pose a significant risk of triggering thrombotic complications in patients with antiphospholipid syndrome (APS). In this report, we present a patient with previously undiagnosed APS who developed unforeseen multiple arterial thromboses following elective surgeries. The patient was a young and otherwise healthy woman who developed multiple arterial thromboses affecting both lower and upper extremities shortly after undergoing breast implant surgery, reduction mammoplasty, and abdominoplasty. Serological studies revealed APS. The patient underwent thrombolytic therapy and thrombectomy of the right subclavian and popliteal artery thromboses. Despite these efforts, digital ischemia progressed resulting in thumb necrosis that ultimately required amputation. This case history illustrates the severe consequences of previously undiagnosed APS in post-surgical settings. It is crucial for clinicians to be aware of potential complications of undiagnosed APS in surgical patients and to recognize how this hypercoagulable syndrome can manifest.</p>

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Multiple Arterial Thromboses in Post-surgical Setting as a Sequala of Previously Undiagnosed Antiphospholipid Syndrome: Case Report

  • 期刊论文

  • 发表日期：

    2025年3月17日

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  • Jonathan Ryan,
  • Momoko Ishizuka,
  • Andrew Schleffer,
  • Husam Alhaddad,
  • Mohammadali M. Shoja,
  • Gary Schwartz

摘要

Surgical interventions pose a significant risk of triggering thrombotic complications in patients with antiphospholipid syndrome (APS). In this report, we present a patient with previously undiagnosed APS who developed unforeseen multiple arterial thromboses following elective surgeries. The patient was a young and otherwise healthy woman who developed multiple arterial thromboses affecting both lower and upper extremities shortly after undergoing breast implant surgery, reduction mammoplasty, and abdominoplasty. Serological studies revealed APS. The patient underwent thrombolytic therapy and thrombectomy of the right subclavian and popliteal artery thromboses. Despite these efforts, digital ischemia progressed resulting in thumb necrosis that ultimately required amputation. This case history illustrates the severe consequences of previously undiagnosed APS in post-surgical settings. It is crucial for clinicians to be aware of potential complications of undiagnosed APS in surgical patients and to recognize how this hypercoagulable syndrome can manifest.