E. coli–Mediated Acute Suppurative Thyroiditis with Thyroid Abscess in a Patient with Urosepsis: Case Report
摘要
Thyroid abscesses are rare modalities of infectious pathology of the thyroid gland. The thyroid is highly resistant to infection due to high iodine content, capsule, and rich vascularity (1). Acute suppurative thyroiditis represents less than 1% of thyroid diseases (2), but if present, could potentially lead to life-threatening airway emergencies apart from endocrine emergencies like thyroid storm. Life-threatening airway compromise or mediastinitis can occur with much higher frequencies from neck infections similar to the presentation. A 62-year-old diabetic female presented with complaints of sudden onset anterior neck swelling and dysphagia of 1 week duration. She had a history of urinary tract infection leading to acute kidney injury and urosepsis 20 days previously, which was managed conservatively by antibiotics. Bacteraemia from the urosepsis spread to thyroid gland leading to acute suppurative thyroiditis and thyroid abscess. The patient developed acute onset painful enlargement of thyroid gland. Incision and drainage of the neck abscess were done along with left thyroid lobectomy and tracheostomy. She developed left vocal cord paresis postoperatively, but the hoarseness improved after 3 months. Regular dressing and parenteral antibiotics against E. coli resulted in complete wound healing in 2 weeks. We found an association of urinary tract infection with thyroid abscess which was confirmed by E. coli positivity in thyroid abscess culture report from the purulent material and previous urine culture reports. In cases of acute suppurative thyroiditis with thyroid abscess, the primary source of infection should be searched and meticulously treated because in majority of cases, it occurs due to bacteriological spread from a distant site in the body.