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<p>Microalgae play essential roles in oxygen production and carbon fixation, and are valuable sources of biofuels and chemicals. They are also widely used in food production, aquaculture, and pharmaceuticals, and interact with bacteria to establish beneficial relationships that promote growth and nutrient cycling. However, pathogenic bacteria, such as <i>Vibrio</i> species, can compete for nutrients and cause diseases that affect microalgal growth. Bacteriophages (phages) have emerged as a promising strategy to selectively target harmful bacteria while preserving beneficial microbial communities, thus offering a viable alternative to antibiotics. This commentary highlights the potential of phage therapy to enhance microalgal health. Despite its promise, this approach may also pose risks of microbial dysbiosis and unintended shifts in community composition, which should be carefully managed to ensure ecological sustainability.</p>

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Phage therapy as a sustainable strategy to promote microalgal health

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年8月6日

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  • Bernardo Veyrand-Quirós,
  • Eduardo Quiroz-Guzmán,
  • Carlos Omar Lomelí-Ortega,
  • Jose Luis Balcazar

摘要

Microalgae play essential roles in oxygen production and carbon fixation, and are valuable sources of biofuels and chemicals. They are also widely used in food production, aquaculture, and pharmaceuticals, and interact with bacteria to establish beneficial relationships that promote growth and nutrient cycling. However, pathogenic bacteria, such as Vibrio species, can compete for nutrients and cause diseases that affect microalgal growth. Bacteriophages (phages) have emerged as a promising strategy to selectively target harmful bacteria while preserving beneficial microbial communities, thus offering a viable alternative to antibiotics. This commentary highlights the potential of phage therapy to enhance microalgal health. Despite its promise, this approach may also pose risks of microbial dysbiosis and unintended shifts in community composition, which should be carefully managed to ensure ecological sustainability.