Scholarlink

<p>The present research synthesized chromium oxide nanoparticles (NPs) with <i>Pleurotus Ostrea</i><i>tus</i> aqueous extract as a reducing and capping agent. The synthesized biogenic nanoparticles’ synthesis, size and crystalline structure were verified using a UV-Vis Spectrophotometer, which revealed an absorption peak at wavelengths between 265 and 371&#xa0;nm. XRD analysis was performed to determine the structure of the nanoparticles and to determine whether they are crystalline or amorphous. XRD analysis showed the crystalline structure of biosynthesized CrO nanoparticles. Furthermore, biological activities demonstrated CrONPs’ excellent therapeutic potential. Compared to antibiotics, the bactericidal activity of CrONPs was tested against three pathogenic bacterial strains (<i>Listeria monocytogenes</i>,<i> Paenibacillus glucanolyticus</i>,<i> and P. aeruginosa</i>). The <i>Listeria monocytogenes and paenibacillus glucanolyticus</i> were found to be the most sensitive strains inhibited at all the different concentrations, while <i>P. aeruginosa</i> was found to be the most resistant strain. Further, a cytotoxicity assay was performed to determine the cytotoxicity potential of <i>Pleurotus ostreatus-mediated</i> CrONPs against newly hatched nauplii of brine shrimps. Vincristine sulfate was a positive control (IC<sub>50</sub>: 5.23&#xa0;µg/mL). The results for CrONPs were recorded as 45.64&#xa0;µg/mL, which is consistent with the positive control vincristine sulfate. The results confirmed the category of general cytotoxicity for greenly synthesized CrONPs.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Biogenic Synthesis of Chromium Oxide Nanoparticles Using Pleurotus Ostreatus Extract Characterization, Antibacterial Activity, and Cytotoxicity Evaluation

  • 期刊论文

  • 发表日期：

    2025年8月28日

查看全文
  • Izraf Ullah,
  • Murad Muhammad,
  • Javed Iqbal,
  • Banzeer Ahsan Abbasi,
  • Naila Inayat,
  • Ibad Ullah,
  • Tabassum Yaseen

摘要

The present research synthesized chromium oxide nanoparticles (NPs) with Pleurotus Ostreatus aqueous extract as a reducing and capping agent. The synthesized biogenic nanoparticles’ synthesis, size and crystalline structure were verified using a UV-Vis Spectrophotometer, which revealed an absorption peak at wavelengths between 265 and 371 nm. XRD analysis was performed to determine the structure of the nanoparticles and to determine whether they are crystalline or amorphous. XRD analysis showed the crystalline structure of biosynthesized CrO nanoparticles. Furthermore, biological activities demonstrated CrONPs’ excellent therapeutic potential. Compared to antibiotics, the bactericidal activity of CrONPs was tested against three pathogenic bacterial strains (Listeria monocytogenes, Paenibacillus glucanolyticus, and P. aeruginosa). The Listeria monocytogenes and paenibacillus glucanolyticus were found to be the most sensitive strains inhibited at all the different concentrations, while P. aeruginosa was found to be the most resistant strain. Further, a cytotoxicity assay was performed to determine the cytotoxicity potential of Pleurotus ostreatus-mediated CrONPs against newly hatched nauplii of brine shrimps. Vincristine sulfate was a positive control (IC50: 5.23 µg/mL). The results for CrONPs were recorded as 45.64 µg/mL, which is consistent with the positive control vincristine sulfate. The results confirmed the category of general cytotoxicity for greenly synthesized CrONPs.