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<p>Gold nanoparticles (AuNPs) were prepared by the reduction of HAuCl<sub>4</sub> with carbazole in sodium dodecyl sulphate (SDS), cetyltrimethylammonium bromide (CTAB), and polyvinylpyrrolidone (PVP) micellar media under sonochemical conditions. Nanoparticle formation and growth were characterized by UV-visible spectroscopy, and particle shape and size were observed by transmission electron microscopy (TEM). The Fourier transform infrared (FT-IR) spectroscopy was used to explore the surface nature of the nanoparticles. The synthesized AuNPs showed a characteristic surface plasmon resonance (SPR) band from 530&#xa0;nm to 560&#xa0;nm, depending on the micellar medium. The TEM image confirmed the spherical shape of AuNP in SDS, whereas anisotropic shapes were observed in CTAB and PVP. It was found that synthesized AuNPs have a significant fluorescence property. This property was used to investigate the potential of these AuNPs in sensing ct-DNA. The article is about the successful development of a green, sonochemical method for synthesizing AuNPs, where carbazole is a good reducing agent and AuNPs exhibit promising biosensing towards ct-DNA.</p>

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Green Sonochemical Synthesis of Gold Nanoparticles by Carbazole and Sensing of ct-DNA

  • 期刊论文

  • 发表日期：

    2025年4月30日

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  • Md. Niharul Alam

摘要

Gold nanoparticles (AuNPs) were prepared by the reduction of HAuCl4 with carbazole in sodium dodecyl sulphate (SDS), cetyltrimethylammonium bromide (CTAB), and polyvinylpyrrolidone (PVP) micellar media under sonochemical conditions. Nanoparticle formation and growth were characterized by UV-visible spectroscopy, and particle shape and size were observed by transmission electron microscopy (TEM). The Fourier transform infrared (FT-IR) spectroscopy was used to explore the surface nature of the nanoparticles. The synthesized AuNPs showed a characteristic surface plasmon resonance (SPR) band from 530 nm to 560 nm, depending on the micellar medium. The TEM image confirmed the spherical shape of AuNP in SDS, whereas anisotropic shapes were observed in CTAB and PVP. It was found that synthesized AuNPs have a significant fluorescence property. This property was used to investigate the potential of these AuNPs in sensing ct-DNA. The article is about the successful development of a green, sonochemical method for synthesizing AuNPs, where carbazole is a good reducing agent and AuNPs exhibit promising biosensing towards ct-DNA.