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<p>Peri-implantitis is a leading cause of dental implant failure, resulting from persistent inflammation and increasing bone resorption caused by microbial colonization. Although standard implant materials, such as Near Alpha-Beta Titanium (αβ) and AISI 316&#xa0;L stainless steel (SS), exhibit mechanical resilience, their limited surface bioactivity impedes long-term osseointegration and infection resistance. This study involved the development and characterization of multifunctional nanocomposite coatings based on fluorapatite-modified zirconia Nanocomposites (NC), utilizing electrophoretic deposition and dip coating methods. Structural and compositional investigations (FTIR, XRD, SEM-EDS) validated effective coating adhesion and uniformity. Surface characteristics were assessed using contact angle measurements, electrochemical evaluations in simulated body fluid and artificial saliva, and cytocompatibility tests by MTT assays. The nanocomposite-coated samples demonstrated greater hydrophilicity, markedly improved corrosion resistance, and positive biological responses. The NC-coated αβ alloy exhibited regulated fluoride ion release, significantly reducing inflammatory reactions and enhancing cell proliferation by 139.0 ± 4.93%. These findings highlight the capability of zirconia-based nanocomposite interfaces to augment implant biofunctionality, suggesting a promising strategy for improving long-term implant success by facilitating osseointegration and mitigating peri-implantitis.</p>

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Fluorapatite-modified zirconia nanocomposite coatings for dental implants: Enhancing osseointegration and protection against peri-implantitis

  • 期刊论文

  • 发表日期：

    2026年7月7日

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  • Fabiola Jemmie Shilparani F.,
  • Aruljothi K.N,
  • Hari Raj K.,
  • Gnanavel S.

摘要

Peri-implantitis is a leading cause of dental implant failure, resulting from persistent inflammation and increasing bone resorption caused by microbial colonization. Although standard implant materials, such as Near Alpha-Beta Titanium (αβ) and AISI 316 L stainless steel (SS), exhibit mechanical resilience, their limited surface bioactivity impedes long-term osseointegration and infection resistance. This study involved the development and characterization of multifunctional nanocomposite coatings based on fluorapatite-modified zirconia Nanocomposites (NC), utilizing electrophoretic deposition and dip coating methods. Structural and compositional investigations (FTIR, XRD, SEM-EDS) validated effective coating adhesion and uniformity. Surface characteristics were assessed using contact angle measurements, electrochemical evaluations in simulated body fluid and artificial saliva, and cytocompatibility tests by MTT assays. The nanocomposite-coated samples demonstrated greater hydrophilicity, markedly improved corrosion resistance, and positive biological responses. The NC-coated αβ alloy exhibited regulated fluoride ion release, significantly reducing inflammatory reactions and enhancing cell proliferation by 139.0 ± 4.93%. These findings highlight the capability of zirconia-based nanocomposite interfaces to augment implant biofunctionality, suggesting a promising strategy for improving long-term implant success by facilitating osseointegration and mitigating peri-implantitis.