Scholarlink

<p>Magnetic nanoalloys offer an intriguing platform for the integration of adjustable magnetic and structural properties at the nanoscale. Although earlier studies on Fe based nanoparticles and Fe-Ni nanoalloys have primarily focused on structure dependent magnetic properties, the present work extends this correlation towards hyperthermia application in Fe<sub>3</sub>Ni alloys with varying size in the nano regime. We have synthesized Fe<sub>3</sub>Ni nanoalloy through hydrothermal technique followed by calcination at 550, 600 and 650&#xa0;°C. The structural analysis through X-ray diffraction (XRD) exhibits a structural transformation from mixed face centered cubic (FCC) and body centered cubic (BCC) phase at former calcination temperatures to a single BCC phase at the highest calcination temperature (650&#xa0;°C). High-resolution scanning electron microscopy (HRSEM) analysis shows agglomerated spherical particles with average size of ~ 35&#xa0;nm indicating polycrystalline nature. Although a soft ferromagnetic behavior is observed irrespective of phase, a high saturation magnetization (M<sub>s</sub>) is obtained in the BCC phase alloy. The hysteresis loops fitted using modified Langevin function demonstrates that the magnetic size obtained from the fitting matches well with the average crystallite size estimated from XRD linewidth. Further, the induction heating performance of the ferrofluid of the nanoalloy calcined at 600&#xa0;°C at varying concentrations show that 10&#xa0;mg/mL formulation steadily reaches the therapeutic hyperthermia temperature (~ 43&#xa0;°C) under an alternating magnetic field (AMF) of 17 mT with a specific absorption rate (SAR) of 75.20&#xa0;W g<sup>− 1</sup>. The cytocompatibility of the ferrofluids examined using MTT assay by implementing fibroblast 3T3 cells displays the optimized Fe<sub>3</sub>Ni nanoalloy ferrofluids in combination with good heating ability and favourable magnetic properties, recommending it as a suitable candidate for treating localized magnetic hyperthermia.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Phase-tuned Fe3Ni soft ferromagnetic nanoalloys for stable and biocompatible magnetic hyperthermia

  • 期刊论文

  • 发表日期：

    2026年7月6日

查看全文
  • Aiswarjya Bastia,
  • Sandeep Kumar Yadav,
  • Ashutosh Kumar Dubey,
  • Chinmaya Mohapatra,
  • N. K. Prasad,
  • Chandana Rath

摘要

Magnetic nanoalloys offer an intriguing platform for the integration of adjustable magnetic and structural properties at the nanoscale. Although earlier studies on Fe based nanoparticles and Fe-Ni nanoalloys have primarily focused on structure dependent magnetic properties, the present work extends this correlation towards hyperthermia application in Fe3Ni alloys with varying size in the nano regime. We have synthesized Fe3Ni nanoalloy through hydrothermal technique followed by calcination at 550, 600 and 650 °C. The structural analysis through X-ray diffraction (XRD) exhibits a structural transformation from mixed face centered cubic (FCC) and body centered cubic (BCC) phase at former calcination temperatures to a single BCC phase at the highest calcination temperature (650 °C). High-resolution scanning electron microscopy (HRSEM) analysis shows agglomerated spherical particles with average size of ~ 35 nm indicating polycrystalline nature. Although a soft ferromagnetic behavior is observed irrespective of phase, a high saturation magnetization (Ms) is obtained in the BCC phase alloy. The hysteresis loops fitted using modified Langevin function demonstrates that the magnetic size obtained from the fitting matches well with the average crystallite size estimated from XRD linewidth. Further, the induction heating performance of the ferrofluid of the nanoalloy calcined at 600 °C at varying concentrations show that 10 mg/mL formulation steadily reaches the therapeutic hyperthermia temperature (~ 43 °C) under an alternating magnetic field (AMF) of 17 mT with a specific absorption rate (SAR) of 75.20 W g− 1. The cytocompatibility of the ferrofluids examined using MTT assay by implementing fibroblast 3T3 cells displays the optimized Fe3Ni nanoalloy ferrofluids in combination with good heating ability and favourable magnetic properties, recommending it as a suitable candidate for treating localized magnetic hyperthermia.