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<p>In the present work, Ti-6Al-4V scaffolds having 10, 20, 30, and 40% porosity were prepared using the powder metallurgy route. The scaffold’s required porosity was achieved using ammonium bicarbonate as a space holder. The density, elastic modulus and compressive strength are found to be decreasing with the increase of porosity. The electrochemical corrosion test of these scaffolds was conducted in simulated body fluid (SBF) – Hank’s balanced salt solution (HBSS). The Ti-6Al-4V scaffold with 40% porosity shows a higher corrosion resistance among the investigated scaffolds. In addition, it exhibits compressive modulus closer to the bone. After the potentiodynamic polarization test, the release of metal ions was estimated by ICP-OES. The results show that Ti and V-concentration in HBSS is well within the tolerance limit for human blood. The Al-concentration is just below the toxic limit. Cell viability studies using osteoblast-like MG63 on porous scaffolds display non-toxicity and good cytocompatibility.</p>

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Investigations into mechanical and corrosion behavior of Ti6Al4V scaffolds prepared using space holder technique

  • 期刊论文

  • 发表日期：

    2025年1月20日

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  • Tapas Kumar Bhanj,
  • Sourav Ganguly,
  • Ann Mary Mathew,
  • Deepak K. Pattanayak,
  • Mayadhar Debata,
  • Tapas Kumar Sahoo,
  • Navin Kumar,
  • Subhra Ranjan Das,
  • Niraj Chawake,
  • Ajit Panigrahi

摘要

In the present work, Ti-6Al-4V scaffolds having 10, 20, 30, and 40% porosity were prepared using the powder metallurgy route. The scaffold’s required porosity was achieved using ammonium bicarbonate as a space holder. The density, elastic modulus and compressive strength are found to be decreasing with the increase of porosity. The electrochemical corrosion test of these scaffolds was conducted in simulated body fluid (SBF) – Hank’s balanced salt solution (HBSS). The Ti-6Al-4V scaffold with 40% porosity shows a higher corrosion resistance among the investigated scaffolds. In addition, it exhibits compressive modulus closer to the bone. After the potentiodynamic polarization test, the release of metal ions was estimated by ICP-OES. The results show that Ti and V-concentration in HBSS is well within the tolerance limit for human blood. The Al-concentration is just below the toxic limit. Cell viability studies using osteoblast-like MG63 on porous scaffolds display non-toxicity and good cytocompatibility.