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Analytical probe for reliable sensing of metformin using cannon ball flower derived fluorescent CDs

  • Pradnya Khandagale,
  • Akshata Pattanshetti,
  • Prasad Mahajan,
  • Rohant Dhabbe,
  • Ashok Ubale,
  • Rajratna Kakade,
  • Sandip Nipane,
  • Sandip Sabale

摘要

Currently, carbon dots (CDs) have emerged as effective and viable sensing probes for detection of drugs owing to their exceptional fluorescence properties. Herein, the present work proposes the green synthesis of CDs using cannon ball (Couropita guianesis) flower petals which is further utilized as the analytical probe for detection of metformin (MTF) drug. The synthesized cannon ball carbon dots (CBCDs) exhibits 1.5 to 3.0 nm size with polycrystalline nature. The obtained CBCDs possess significant fluorescence property at 240 nm. Further, the prepared CBCDs demonstrate potential for sensing MTF in the range 5 µmolL−1 to 50 µmolL−1, with low detection limit of 0.79 µmolL−1 and low quantization limit of 2.3988 µmolL−1. The proposed work offers excellent, cost-effective and sustainable sensing probe for the quantitative detection of MTF.

Graphical abstract