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Purpose <p>To evaluate the relationship between caregiver burden and in-hospital mortality in older adults.</p> Methods <p>A prospective observational cohort including 252 adults aged ≥ 65&#xa0;years hospitalized at the Hospital General de Zona No. 2 (Saltillo, Mexico) from May to July 2025. Caregiver burden was assessed at admission using the&#xa0;Spanish-validated 22-item Zarit Burden Interview. Patients were followed until discharge or death to determine in-hospital mortality.</p> Results <p>A total of 252 patients were included, with a mean age of 74.6 ± 7.3&#xa0;years; 56.7% were women. Overall mortality was 22.6%. Mortality by burden was none—10.4% (20/192), mild—48.6% (18/37), severe—82.6% (19/23); <i>p</i> &lt; 0.001. After adjustment, mild burden had RR = 4.23 (95% CI 2.47–7.21; <i>p</i> &lt; 0.001), severe burden RR = 5.88 (95% CI 3.58–9.67; <i>p</i> &lt; 0.001). Each additional year of age increased mortality risk by 3.5% (RR = 1.035; 95% CI 1.012–1.058; <i>p</i> = 0.003).</p> Conclusions <p>Caregiver burden was independently associated with increased in-hospital mortality. Systematic caregiver assessment should be considered in geriatric practice.</p>

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Caregiver burden and in-hospital mortality in older adults: insights from a Mexican single-center Latin American study

  • 期刊论文

  • 发表日期：

    2025年11月19日

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  • Lizeth García Barrera,
  • Ana Sofía Sánchez Balderas,
  • Xitlali Guadalupe Granados Silva,
  • Itzel López Topete,
  • Luis Carlos Martínez Reyna,
  • Rodrigo González Aguirre

摘要

Purpose

To evaluate the relationship between caregiver burden and in-hospital mortality in older adults.

Methods

A prospective observational cohort including 252 adults aged ≥ 65 years hospitalized at the Hospital General de Zona No. 2 (Saltillo, Mexico) from May to July 2025. Caregiver burden was assessed at admission using the Spanish-validated 22-item Zarit Burden Interview. Patients were followed until discharge or death to determine in-hospital mortality.

Results

A total of 252 patients were included, with a mean age of 74.6 ± 7.3 years; 56.7% were women. Overall mortality was 22.6%. Mortality by burden was none—10.4% (20/192), mild—48.6% (18/37), severe—82.6% (19/23); p < 0.001. After adjustment, mild burden had RR = 4.23 (95% CI 2.47–7.21; p < 0.001), severe burden RR = 5.88 (95% CI 3.58–9.67; p < 0.001). Each additional year of age increased mortality risk by 3.5% (RR = 1.035; 95% CI 1.012–1.058; p = 0.003).

Conclusions

Caregiver burden was independently associated with increased in-hospital mortality. Systematic caregiver assessment should be considered in geriatric practice.