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Purpose <p>Our aim is to analyse whether the Frail-VIG index (frailty index validated in the geriatric population) maintains its predictive capacity for mortality in geriatric patients with femur fracture (FF).</p> Methods <p>Observational prospective cohort study including patients over 65&#xa0;years of age consecutively admitted for FF to a community hospital. Patients were classified according to their frailty degree into three groups: none/initial frailty (Frail-VIG index &lt; 0.36), moderate frailty (Frail-VIG index: 0.36–0.50), and advanced frailty (Frail-VIG index &gt; 0.50). The association between 12-month mortality and frailty was estimated in an adjusted Cox regression model and expressed as hazard ratio (HR) with 95% confidence interval (95% CI). ROC curves were analysed to assess the prognostic capacity of Frail-VIG index. The reliability and feasibility were also assessed.</p> Results <p>150 patients were included (78% women and mean age 88&#xa0;years). Patients with advanced frailty had more geriatric syndromes and comorbidities and worse cognitive, emotional, and functional status. In-hospital and 30-day mortality were similar between the three groups. After 12&#xa0;months of follow-up, all-cause mortality was higher in patients with moderate and advanced frailty with an adjusted HR (95% CI) of 3.1 (1.33–7.43; <i>p</i> = 0.009) and 3.93 (1.52–10.1; <i>p</i> = 0.005), respectively. The under the ROC curve area at 12&#xa0;months was 0.71 (0.62–0.80). The intraclass correlation coefficient for reliability was 0.891 (0.804–0.891) and the feasibility showed a mean (SD) of 4.83 (1.39) min.</p> Conclusion <p>The Frail-VIG index has a good predictive capacity for 12-month mortality in geriatric population with FF and also shows very good reliability and feasibility.</p>

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Validation of the Frail-VIG frailty index in geriatric population with femur fracture

  • 期刊论文

  • 发表日期：

    2025年2月26日

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  • Gemma Badosa-Collell,
  • Joan Carles Trullàs,
  • Cristina Moreno,
  • Eva Ruiz-Ruiz,
  • Jordi Amblàs-Novellas

摘要

Purpose

Our aim is to analyse whether the Frail-VIG index (frailty index validated in the geriatric population) maintains its predictive capacity for mortality in geriatric patients with femur fracture (FF).

Methods

Observational prospective cohort study including patients over 65 years of age consecutively admitted for FF to a community hospital. Patients were classified according to their frailty degree into three groups: none/initial frailty (Frail-VIG index < 0.36), moderate frailty (Frail-VIG index: 0.36–0.50), and advanced frailty (Frail-VIG index > 0.50). The association between 12-month mortality and frailty was estimated in an adjusted Cox regression model and expressed as hazard ratio (HR) with 95% confidence interval (95% CI). ROC curves were analysed to assess the prognostic capacity of Frail-VIG index. The reliability and feasibility were also assessed.

Results

150 patients were included (78% women and mean age 88 years). Patients with advanced frailty had more geriatric syndromes and comorbidities and worse cognitive, emotional, and functional status. In-hospital and 30-day mortality were similar between the three groups. After 12 months of follow-up, all-cause mortality was higher in patients with moderate and advanced frailty with an adjusted HR (95% CI) of 3.1 (1.33–7.43; p = 0.009) and 3.93 (1.52–10.1; p = 0.005), respectively. The under the ROC curve area at 12 months was 0.71 (0.62–0.80). The intraclass correlation coefficient for reliability was 0.891 (0.804–0.891) and the feasibility showed a mean (SD) of 4.83 (1.39) min.

Conclusion

The Frail-VIG index has a good predictive capacity for 12-month mortality in geriatric population with FF and also shows very good reliability and feasibility.