<p>La Grotte des Contrebandiers, which contains Middle Stone Age (MSA) occupations dating to Marine Isotope Stage (MIS) 5 and Later Stone Age (LSA) occupations in MIS 2, presents an opportunity to investigate the local impacts of late Pleistocene climate variability on the subsistence strategies of human groups in the Atlantic coastal region of Morocco. This study uses stable oxygen isotopes from large herbivore tooth enamel (δ¹⁸O_enamel values) to explore shifts in precipitation regimes and water deficit in plants through time at the site. In addition, δ¹⁸O_enamel values are paired with marine mollusk abundance data to explore variation in coastal resource use during climate intervals with variable sea levels. We find that δ¹⁸O_enamel values among evaporation-sensitive (ES) and evaporation-insensitive (EI) taxa reveal distinctions between MIS 2 and 5 as well as variation within MIS 5 consistent with orbital-scale climate shifts. Furthermore, we find that during climate intervals with higher inferred sea levels, marine resources were either incorporated into diets more frequently or less field processing occurred. Despite climate variability recorded in δ¹⁸O_enamel proxies, mammalian species composition among faunal assemblages at Contrebandiers do not vary drastically, indicating persistence of mixed scrubland-grassland habitats through time. Human diets at the site were affected most strongly by physical modification of coastal geography than by other climate factors, given that vegetation and animal communities of the Moroccan littoral generally had sufficient ecological flexibility to cope with local climate fluctuations in the late Pleistocene.</p>