<p>Endoscopic resection procedures and the resolution of endoscopes have advanced rapidly in recent years, so that today we are able to remove colorectal lesions and early cancers in a&#xa0;minimally invasive and curative manner that were previously reserved for surgery. However, as interventional options increase, so do the demands on the interventionalist to use the most appropriate technique for a&#xa0;given lesion. In addition to technical skills, which range from simple snare polypectomy to complex endoscopic submucosal dissection (ESD), in-depth knowledge of risk assessment of various colorectal lesions is required. A&#xa0;systematic assessment, including virtual chromoendoscopy, can help remove high-risk lesions with the appropriate degree of invasiveness and lower-risk lesions as gently as possible for the patient. It is also important to identify lesions without malignancy potential, because not everything that is removable actually needs to be removed. Since many screening colonoscopies are now performed in outpatient settings, where technical equipment, time management, and risk management may differ significantly from those in the inpatient setting, it is all the more important that there is good communication between the inpatient and outpatient settings. An endoscopy network between these realities promotes this communication, shortens patient waiting times, and reduces the rate of unnecessary biopsies of lesions that are generally amenable to endoscopic removal. Such collaborations can also contribute significantly to increasing acceptance and participation in screening colonoscopies and, in the long term, reducing the incidence and mortality of colon cancer.</p>