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<p>This study introduces a 1 × 1 × 14&#xa0;mm millimeter-scale medical robot composed of magnetic nanoparticles and controlled by an external magnetic field. Its helical walking structure and steering mechanism enable navigation and drug delivery. Constructed from biocompatible N-isopropylacrylamide hydrogel, the robot ensures flexibility and compatibility with biological environments. The design of the external magnetic control system was guided by theoretical considerations, including the geometric structure and estimated resonance frequency, providing a foundation for parameter selection. Experimental results confirmed high accuracy, efficient propulsion, and controllable drug release in simulated vascular environments, demonstrating the potential for biomedical applications.</p>

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Magnetically controlled helix-driven millimeter-scale medical robot with multifunctional nanoparticle for precision-targeted drug delivery

  • 期刊论文

  • 发表日期：

    2025年8月15日

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  • Yuhui Xu

摘要

This study introduces a 1 × 1 × 14 mm millimeter-scale medical robot composed of magnetic nanoparticles and controlled by an external magnetic field. Its helical walking structure and steering mechanism enable navigation and drug delivery. Constructed from biocompatible N-isopropylacrylamide hydrogel, the robot ensures flexibility and compatibility with biological environments. The design of the external magnetic control system was guided by theoretical considerations, including the geometric structure and estimated resonance frequency, providing a foundation for parameter selection. Experimental results confirmed high accuracy, efficient propulsion, and controllable drug release in simulated vascular environments, demonstrating the potential for biomedical applications.