<p>Aluminum alloys are crucial in transportation applications such as aviation, maritime, and automobiles in the structure of planes, gliders, bicycles. To improve the stability and resources of aluminum alloy, additional ingredients are mixed with pure alumina. This study focuses on MHD three-dimensional hybrid nanofluid flow through a bidirectional linearly extending sheet that contains AA7072 alloys with 98% Al, 1% zinc and AA7075 alloys with 1–2% copper, 90% aluminum, 2–3% magnesium, and 5–6% zinc, along with convective boundary conditions. In the present study, gyrotactic microorganisms are also considered. The physical model is explained in the form of PDEs, which are then transformed into a system of ODEs by using suitable transformations. A powerful semi-analytical technique HAM is utilized to solve the system and the results are explained in graphical and tabular ways. Major findings from the work is the impact of nanoparticle concentration, gyrotatic microorganisms and MHD on fluid flow behavior. The quantitative conclusion of the study is that the increasing of nanoparticle concentration decrease the thickness of the thermal boundary layer approximately 12%.however a sharp enhancement is found in skin friction for magnetic field. Also, the findings show that the velocity plot along the primary direction decrease with increasing value of stretching parameter, however an opposite behavior is noted in velocity profile along secondary direction. Similarly, thermophoretic and Brownian motion factors effect are examined on concentration and temperature profile, which shows an increasing sketch. Moreover, the results show that the flow of hybrid nanofluid is more affected as related to nanofluid. This study are beneficial in optimizing heat and mass transfer in various areas such as thermal management, cooling system, biomedical engineering, bioreactors and drug delivery systems.</p>