<p>Suicide risk is elevated among vulnerable populations. We examined two forms of internalization (i.e., self-blame, self-disgust) and externalization (i.e., other-blame, societal-disgust) and their associations with suicidal ideation (SI) in two studies. In Study 1 (<i>n</i> = 967), participants with mood and/or anxiety disorders completed self-report measures at admission and discharge on self-blame, other-blame, and SI. Study 2 (<i>n</i> = 295) investigated similar constructs among a sexual minority sample, with the addition of covariates including internalized homophobia, homophobia experiences, perceived burdensomeness, and thwarted belongingness. In Study 1, self-blame at admission and discharge, but not other-blame at admission or discharge, was significantly associated with SI. Furthermore, their interaction at discharge was significant such that SI was highest for those high in self-blame and low in other-blame. Longitudinally, neither form of blame at admission was associated with SI at discharge, nor was their interaction. In Study 2, self-disgust, societal-disgust, and their interaction were significantly associated with SI beyond self-blame and other covariates. Contrary to Study 1, the form of the interaction was such that SI was highest for those high in both self-disgust and societal-disgust. Significant findings were cross-sectional; thus, future research should longitudinally test brief intervals (e.g., hours to days) to better understand these associations. These studies provide some evidence that self-blame and self-disgust, more so than other-blame and societal-disgust, may be risk factors for SI in clinical and sexual minority groups.</p>