<p>This paper addresses the Integrated Lot Sizing and Scheduling Problem (ILSP) within a manufacturing context that produces a variety of products, sources raw materials from multiple suppliers, offers various discounts, and incorporates different modes of transportation. The model also accounts for setups that are independent of product sequence for each type of product, as well as setups that exhibit transitional dependencies between product families based on sequence. The proposed model aims to simultaneously determine the purchase quantity, production quantity, and production sequence to maximize total profit. To tackle the ILSP, a mixed integer nonlinear programming (MINLP) model has been developed, incorporating factors such as a hybrid production line, reprocessing of defective products, and energy consumption. In the hybrid production line, manufacturing occurs through both a traditional production line and a green production line, each characterized by distinct process times, product defect rates, and electrical energy consumption. The findings indicate that variations in process time, defect rates, and energy consumption significantly impact total profit. Additionally, the adoption of green technology has the potential to enhance the production process by speeding up production, reducing defect rates, improving energy efficiency, accelerating setups, and minimizing overall energy consumption.</p>