<p>The study aims to examine the adoption of Industry 4.0 technologies in the manufacturing industry and their impact on sustainability. A systematic Literature review was conducted to identify the application and impact of Industry 4.0 in the manufacturing industry. The results showed that Industry 4.0 technologies have significantly contributed to sustainability in the manufacturing sector. Internet of Things (IoT), artificial intelligence (AI), big data analytics (BDA), radio frequency identification (RFID), enterprise resource planning (ERP), and the use of robotics and sensors are the most prominent technologies used in the manufacturing industry. The results also indicated some key challenges, which include higher investment costs, resistance in adoption of technologies, lack of research, Limited awareness, skill gap, and insufficient qualified and skilled human resources. The study provides valuable insight to businesses and policymakers. Industry 4.0 technologies have the potential to solve functional barriers in the manufacturing industry, enhancing efficiency and improving sustainable performance.</p>