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Background <p>The aim of this study was to report a rare case of oral leiomyoma (OLM), treated with a high-power diode laser.</p> Case report <p>A 39-year-old man presented with a submucosal nodule on ventral surface of tongue, approximately 1 cm in diameter, with a four-month history. Excisional biopsy was performed under local anesthesia using a high-power diode laser (980nm, 2W, 605.85J). Histopathological examination revealed a proliferation of ovoid and spindle-shaped cells with numerous blood vessels. Immunohistochemistry showed strong positivity for alpha–smooth muscle actin (α-SMA) and moderate Ki-67 positivity, confirming the diagnosis of OLM. Postoperative recovery was satisfactory, with no infection, and no recurrence after 19 months of follow-up.</p> Conclusion <p>In this case, the high-power diode laser was effective, providing adequate hemostasis, reduced edema, and satisfactory healing. This appears to be the first reported case of OLM treated with high-power diode laser, supporting its use as a safe therapeutic alternative.</p>

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High-power diode laser as a therapeutic approach for oral leiomyoma: a rare case report

  • 期刊论文

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  • 发表日期：

    2026年7月30日

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  • Lucas Lopes Maynart,
  • Diego Filipe Bezerra Silva,
  • Rayssa Emelly Alves de Lacerda,
  • Cassiano Francisco Weege Nonaka,
  • Jozinete Vieira Pereira,
  • Pollianna Muniz Alves,
  • Daliana Queiroga de Castro Gomes

摘要

Background

The aim of this study was to report a rare case of oral leiomyoma (OLM), treated with a high-power diode laser.

Case report

A 39-year-old man presented with a submucosal nodule on ventral surface of tongue, approximately 1 cm in diameter, with a four-month history. Excisional biopsy was performed under local anesthesia using a high-power diode laser (980nm, 2W, 605.85J). Histopathological examination revealed a proliferation of ovoid and spindle-shaped cells with numerous blood vessels. Immunohistochemistry showed strong positivity for alpha–smooth muscle actin (α-SMA) and moderate Ki-67 positivity, confirming the diagnosis of OLM. Postoperative recovery was satisfactory, with no infection, and no recurrence after 19 months of follow-up.

Conclusion

In this case, the high-power diode laser was effective, providing adequate hemostasis, reduced edema, and satisfactory healing. This appears to be the first reported case of OLM treated with high-power diode laser, supporting its use as a safe therapeutic alternative.