<p>Plant disease decreases the yield and quality of food, fiber, and biofuel as agriculture struggles to meet the ever-growing demands of the world’s fast-rising population. Farmers invest substantial resources in disease management; however, inadequate technical support and improper practices often result in ineffective control, environmental pollution, and health concerns. Crop ecosystems, which typically exhibit lower biodiversity than natural ecosystems, are more vulnerable to pathogen spread and disease outbreaks. Mineral nutrients are necessary for the growth and development of the plants as well as microbes, and they play a key role in plant–disease interactions. The impact of mineral nutrition on disease resistance is contingent upon the specific plant pathogen system and the intricate interplay between multiple nutrients. Nutrient availability can modify plant metabolism, regulate the synthesis of defensive compounds, and alter susceptibility or resistance to infection. This review provides an overview of current knowledge on how mineral nutrients influence fungal diseases in plants. It focuses on their roles in enhancing resistance, improving tolerance, and suppressing disease development. It further discusses the physiological and biochemical mechanisms through which balanced nutrient management strengthens plant defense responses. Understanding the relationship between mineral nutrition and plant disease can support the development of integrated nutrient management strategies aimed at improving crop productivity and promoting sustainable agriculture.</p>