Objectives <p>Dysgraphia and dyslexia are two specific learning disorders affecting writing and reading, respectively. Although the existing studies reflect on the characteristic features of dysgraphia and dyslexia, they did not comprehensively substantiate whether dysgraphia is a comorbidity of dyslexia or an independent disorder. This review aims to fill this gap by comparatively analyzing dysgraphia and dyslexia, with a focus on their cognitive and neural underpinnings.</p> Methods <p>A theoretical synthesis approach was employed to offer a comparative analysis of dysgraphia and dyslexia by probing into the complex cognitive mechanisms supporting writing and reading, their disruptions, and the neuroanatomy implicated in dysgraphia and dyslexia.</p> Results <p>The review provides insights into the comorbid nature of dysgraphia, while also acknowledging the distinct features that contribute to their independent existence.</p> Conclusions <p>This integrative perspective on dysgraphia and dyslexia could advance our understanding of these conditions and guide future research in effective diagnosis and pertinent interventions.</p>