Radioisotopes are now widely used in many different fields due to technological advancements. One of these fields is nuclear medicine. Many radioisotopes are used for diagnosis and treatment in nuclear medicine. The suitable physical properties of \(^{76}\) Br isotopes for imaging in positron emission tomography (PET) have led researchers to study their potential production from different reaction channels. This study aimed to determine the parameters that can serve as a basis for experimental studies: production cross-sections, reaction yields, and total activity. In this context, we investigated some possible proton-induced production mechanisms of \(^{76}\) Br using level density models. For this purpose, the Constant Temperature Fermi Gas Model (CTFGM), Back Shifted Fermi Gas Model (BSFGM), and Generalised Superfluid Model (GSM) models within the framework of TALYS 1.95 nuclear reaction code have been used for \(^{Nat}\) Se(p,xn) \(^{76}\) Br reaction channels. The calculated production cross-section values up to 60 MeV beam energy are found to agree with the available data in the literature. Furthermore, the reaction yields as a function of beam energy and total activation values as a function of irradiation time have been carried out.
