Let \(f(x)=x^{n}+ax^{3}+bx+c\) be the minimal polynomial of an algebraic integer \(\theta \) over the rationals with certain conditions on a, b, c, and n. Let \(K={\mathbb Q}(\theta )\) be a number field and \(\mathcal {O}_{K}\) be the ring of integers of K. In this article, we characterize all the prime divisors of the discriminant of f(x) which do not divide the index of \({\mathbb Z}[\theta ]\) in \(\mathcal {O}_{K}.\) As an interesting corollary, we establish necessary and sufficient conditions for \({\mathbb Z}[\theta ]\) to be integrally closed. Finally, we investigate the types of solutions to certain differential equations associated with the polynomial f(x).